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[Dysphagia] Difficult case- consistent choking
- Subject: [Dysphagia] Difficult case- consistent choking
- From: sorriso at adelphia.net (sorriso@adelphia.net)
- Date: Fri Dec 30 19:29:39 2005
Is this Dr. Irene Campbell-Taylor with a new email address? I hope I'm not "outing" you if you are trying to preserve anonymity but this response is classic Irene (and if you're trying to hide you should have chosen a different email name!) but it's unlike her not to sign her name in response.
Linda A. Zanchi, MA CCC-SLP
---- Drirenect@aol.com wrote:
>
> Given her meds and Hx I would guess that she has Sjogren syndrome ( dry eyes
> and OA) ? the xerostomia contributing significantly to both GERD and
> choking. Most of her meds will make the xerostomia worse and she may well be
> chronically dehydrated ? more likely hypovolemic hyponatremia than hypernatremia
> given her age and meds.. Her hydration status needs to be checked and monitored
> consistently ? food should be moist and cohesive since xerostomia alone may
> intermittently disrupt the swallow. Scleroderma is also commonly associated
> with Sjogren. Elderly persons often do not c/o xerostomia and you indicate some
> possible cognitive impairment. It is also not possible to identify
> dehydration by appearance alone.
> The falls could be due to meds (ataxia) or to hemodynamic instability
> related to dehydration.
> See:
> Bouman WP; Pinner G; Johnson H . Incidence of selective serotonin reuptake
> inhibitor (SSRI) induced hyponatraemia due to the syndrome of inappropriate
> antidiuretic hormone (SIADH) secretion in the elderly. Int J Geriatr
> Psychiatry, 13:12-15 1998
> In a sample of 32 eldely patients taking SSRIs, four developed symptomatic
> hyponatremia due to SIADH (12.5%). Four more developed asymptomatic
> hyponatremia following introduction of an SSRI (12.5%), although laboratory
> confirmation of SIADH was lacking. This study shows a high incidence in elderly patients
> of this potentially dangerous complication. The use of SSRI?s in elderly
> people must include monitoring of electrolytes for early detection and reduction
> of morbidity.
> Nederfors T. Xerostomia: prevalence and pharmacotherapy. With special
> reference to beta-adrenoceptor antagonists. Swed Dent J Suppl 116:1-70.1996.
> The effects of one week on propranolol and atenolol were compared with
> placebo in three different trials by 600 subjects and 68 controls. Saliva
> composition but not flow rates were affected by the drugs, most changes being in
> total protein composition and amylase , both significantly decreased with the
> saliva becoming thicker than normal.
> Lewis IK; Hanlon JT; Hobbins MJ; Beck JD. Use of medications with potential
> oral adverse drug reactions in community-dwelling elderly. Spec Care Dentist
> 13:171-6.1993.
> Prevalence and indicators of medication use with potential oral health
> implications among 4,163 subjects were studied. Medications were grouped into
> seven potential oral adverse drug reaction categories. Eighty percent of
> participants were taking at least one medication from any of the seven categories.
> Drugs with the potential to cause xerostomia were taken by 56.1%, abnormal
> hemostasis by 51.7%, soft tissue reactions by 23.4%, taste changes by 11.0%,
> alteration in host resistance by 8.7%, gingival overgrowth by 5.0%, and movement
> disorders by 2.4% of participants
> Korsten MA; Rosman AS; Fishbein S; Shlein RD; Goldberg HE; Biener A. Chronic
> xerostomia increases esophageal acid exposure and is associated with
> esophageal injury. Am J Med 90:701-6.1991.
> This was a study of sixteen male patients with xerostomia secondary to
> radiation for head and neck cancers or medications. There were nineteen
> age-matched male control subjects with comparable histories. Clearance of acid from the
> esophagus and 24-hour intraesophageal pH were abnormal in patients with
> xerostomia. Symptoms and signs of esophagitis were significantly more frequent.
> As swallowing saliva is the major means of esophageal clearance, chronic
> xerostomia may predispose to esophageal injury by decreasing the clearance of acid
> from the esophagus and altering intraesophageal pH
> And there are many more similar.
>
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