|
[Date Prev][Date Next]
[Chronological]
[Thread]
[Top]
[Dysphagia] RE: how much water
Pepcid is described as follows:
Pepcid - famotidine
Aspiration Pneumonia Prevention
take 2 tablets (40mg) by oral route the night before surgery
take 2 tablets (40mg) by oral route the morning of surgery
take 2 tablets (40mg) by oral route the night before surgery
take 2 tablets (40mg) by oral route the morning of surgery
(This is actually for the prevention of aspiration pneumonitis not pneumonia .)
Recent indicators for the PPIs are that they are realted to pneumonia because the supporession of gastric acid and the alteration of stomach contents to alkaline instead of acid does not kill the oral bacteria that are normallt swallowed allowing them to be either refluxed and/or to "climb" the esophagus and enter the airway. Famotidine may be acting in thsi woman in the same way.
Its description continiues:
Famotidine is used orally for the treatment of active duodenal or gastric ulcer, gastroesophageal reflux disease, endoscopically diagnosed erosive esophagitis, and as maintenance therapy for duodenal ulcer. Oral famotidine also is used for the management of pathological GI hypersecretory conditions. IV famotidine is used in hospitalized individuals with pathological GI hypersecretory conditions or intractable ulcers, or when oral therapy is not feasible.
Famotidine is used to provide short-term symptomatic relief of gastroesophageal reflux disease (GERD). Famotidine also is used for short-term treatment of esophagitis associated with gastroesophageal reflux, including endoscopically proven erosive or ulcerative disease. By increasing gastric pH, H2-receptor antagonists have relieved heartburn and other symptoms of reflux and have been associated with somewhat higher healing rates of endoscopically proven esophagitis when compared with placebo and have reduced antacid consumption.
acellucc@bidmc.harvard.edu wrote:
She doesnt have copious amounts of oral flora, there were high numbers of oropharyngeal flora cultured in her sputum samples twice, and per the MD, based on the cells and info retreived from the cultures, there was not a high suspicion for any contaminate or false info. She doesnt seem to have any issues with regards to secretion management, and her cough is productive. She'd had the cough and fevers several days prior to the admission. She reported her cough was actually worse in the evening, and not post prandial. She was only on Pepcid, but no other PPI. I was not aware of Ilene's post that even the lower hematocrit could have left her immunocompromised enough to be susceptible to nocturnal aspiration of secretions.
________________________________
From: pressmah@sjhmc.org [mailto:pressmah@sjhmc.org]
Sent: Tue 3/15/2005 11:19 AM
To: Cellucci,J. Alexandria (BIDMC - Surgery); dysphagia@b9.com
Subject: RE: [Dysphagia] RE: how much water
Why does she have copious amounts of oral flora? A program of meticulous
oral hygiene-with a toothbrush not a toothette (need to have friction) along
with a dental consult to remove any decayed teeth might be the greatest help
to her
Hilda Pressman, MA, CCC SLP BRS-S
Board Recognized Specialist in Swallowing and Swallowing Disorders
-----Original Message-----
From: acellucc@bidmc.harvard.edu [mailto:acellucc@bidmc.harvard.edu]
Sent: Monday, March 14, 2005 2:51 PM
To: dysphagia@b9.com
Subject: [Dysphagia] RE: how much water
Along the lines of these postings, I have a question with regards to a pt we
recently were asked to see, whose first two chest films have reportedly been
negative for evidence of pna, they are planning to run more films to follow
this, but was admitted with fever, productive cough, dyspnea, sat @88% on
RA, requiring O2, who had 2 sputum cultures (+) for oropharyngeal flora, RLL
rhonchi, r/o for the flu, but the working dx thus far is pna (per MD team,
not me, mind you). She does not have any oropharyngeal dysphagia based on
exams at the bedside and under fluoroscopy (though there is evidence of a
hiatal hernia - but if there was reflux occurring occultly - would the
sputum have oropharyngeal flora in it?). PMH includes: aortic stenosis, s/p
AVR/Pacer, afib, iron deficiency anemia, s/p L CEA, s/p L MCA CVA '00 w/ h/o
seizure, temporal arteritis, depression, diverticulae, hemorrhoids,
essential tremor, cervical stenosis, h/o GIB, h/o scarlet fever, s/p
hysterectomy, s/p kidney!
removal. Also had a dropping hematocrit recently requiring 1u PRBC.
So my question is, in this pt who is not presenting with any difficulty
taking po's, is the presence of "copious amounts of oropharyngeal flora (per
MD)" potentially due to aspiration while sleeping?? Any thoughts would be
greatly appreciated, as I am just curious about this pt, mind you we are not
restricting her po's on our end in any way, I am just wondering how this
could have come about in a pt who is not significantly immunocompromised,
ambulatory, living at home (with some assistance, but certainly not
dependent for her care).
Any thoughts?
alex
Message: 2
Date: Mon, 14 Mar 2005 05:56:11 -0800 (PST)
From: Irene Campbell-Taylor
Subject: RE: [Dysphagia] Re: how much water?
To: Jai Gupta , Dysphagia@b9.com
Message-ID: <20050314135611.47138.qmail@web14023.mail.yahoo.com>
Content-Type: text/plain; charset=us-ascii
Jai Gupta wrote:
Hi all, I am really worried when people make a generalist comment that "each
patient receives his or her requisite amount of water every day"..
*** That was the OPPOSITE of a general comment - please note "his or her
requisite amount" - individualized and we DO have methods of determining how
mucha given individual needs. Please read the medical, nursiing and
physiological literature on hydration.
..we don't have evidence do we? I have come across so many elderly citizens
who do not drink a sip of water but live on tea or cordial some on bear .
*** And are chronically dehydrated as all of the above are DIURETIC.
....but these are rare cases ..
*** These are COMMON cases .
and there are obvious signs of asp pneu
*** Aspiration pneumonia is one of the most difficult diagnoses to make in a
living person.Please note the following from, arguably, the world's expert
on aspiration pneumonia and aspiration pneumonitis:
Aspiration pneumonia
John G Bartlett, MD
Co-Editor-in-Chief - Infectious Diseases
Professor of Medicine
Johns Hopkins University School of Medicine
INTRODUCTION - Aspiration is a common event even in healthy individuals and
usually resolves without detectable sequelae. Markers placed in the stomach
can often be detected in the lungs of healthy persons using scintigraphic
methods.
[Berson, W, Adiani, J. "Silent" regurgitation and aspiration of gastric
contents during anesthesia. Anesthesiology 1954; 15:644.]
Aspiration pneumonia refers to the pulmonary consequences resulting from the
abnormal entry of fluid, particulate exogenous substances, or endogenous
secretions into the lower airways. There are usually two requirements to
produce aspiration pneumonia:
Compromise in the usual defenses that protect the lower airways including
glottic closure, cough reflex, and other clearing mechanisms
An inoculum deleterious to the lower airways by a direct toxic effect,
stimulation of an inflammatory process from a large enough bacterial
inoculum, or obstruction due to a sufficient volume of material or
particulate matter
Most pneumonia arises following the "aspiration" of microorganisms from the
oral cavity or nasopharynx. The term aspiration pneumonia should be reserved
for pneumonitis resulting from the altered clearance defenses noted above.
The pathogens which commonly produce pneumonia, such as Streptococcus
pneumoniae, Haemophilus influenzae, Gram negative bacilli, and
Staphylococcus aureus, are relatively virulent bacteria so that only a small
inoculum is required and the aspiration is usually subtle.
A true aspiration pneumonia, by convention, usually refers to an infection
caused by less virulent bacteria, primarily anaerobes, which are common
constituents of the normal flora in a susceptible host prone to aspiration.
The predisposing conditions, clinical syndromes, diagnosis, and treatment of
aspiration pneumonia will be reviewed here. Community-acquired pneumonia,
nosocomial pneumonia, pneumonia due to specific pathogens, empyema, and lung
abscess are discussed separately. (See related topic reviews).
PREDISPOSING CONDITIONS - Conditions that predispose to aspiration pneumonia
include:
Reduced consciousness, resulting in a compromise of the cough reflex and
glottic closure
Dysphagia from neurologic deficits
Disorders of the upper gastrointestinal tract including esophageal
disease, surgery involving the upper airways or esophagus, and gastric
reflux
Mechanical disruption of the glottic closure or cardiac sphincter due to
tracheostomy, endotracheal intubation, bronchoscopy, upper endoscopy, and
nasogastric feeding
Pharyngeal anesthesia, and miscellaneous conditions such as protracted
vomiting, large volume tube feedings, feeding gastrostomy, and the recumbent
position
These conditions all share properties of frequent or large volume aspiration
which increase the probability of developing aspiration pneumonitis . A
number of interventions (eg, positioning, dietary changes, drugs, oral
hygiene, tube feeding) have been proposed to prevent aspiration, especially
in elderly patients. However, a systematic review of such measures found
insufficient data to assess effectiveness
Interventions to prevent aspiration pneumonia in older adults: a systematic
review.
Loeb MB; Becker M; Eady A; Walker-Dilks C
J Am Geriatr Soc 2003 Jul;51(7):1018-22.
A systematic review was conducted to assess the effectiveness of the
following interventions for prevention of aspiration pneumonia (AP) in older
adults: compensatory strategy/positioning changes, dietary interventions,
pharmacologic therapies, oral hygiene, and tube feeding. Data sources
included a key word search of the MEDLINE, EMBASE, Cochrane Library, CINAHL,
and HealthSTAR databases and hand searches of six journals. Reference lists
of relevant primary and review articles were searched. Studies included were
randomized, controlled trials (RCTs) enrolling adults aged 65 and older at
risk of and assessed for AP. Two investigators extracted data on population,
intervention, outcomes, and methodological quality. Of the 17 identified
RCTs, eight met the selection criteria, two addressed dietary management or
compensatory swallowing, two assessed pharmacological therapies, one
assessed oral hygiene, and three assessed tube feeding. None of the eight
trials reported use of bl!
inding,
and allocation concealment was unclear in five. Use of amantadine prevented
pneumonia in one trial of nursing home residents. The antithrombotic agent
cilostazol prevented AP in another trial but resulted in excessive bleeding.
Insufficient data exist to determine the effectiveness of positioning
strategies, modified diets, oral hygiene, feeding tube placement, or
delivery of food in preventing AP. Considering how common the problem of AP
is in older adults, larger, high-quality RCTs on the effectiveness of
preventive interventions are warranted.
AD - Department of Clinical Epidemiology and Biostatistics, McMaster
University, Hamilton, Ontario, Canada.
Dr I Campbell-Taylor
Clinical Neuroscientist
Exclusive Distributor:
www.interactivetherapy.com
------------------------------
_______________________________________________
Dysphagia mailing list
Dysphagia@b9.com
http://lists.b9.com/mailman/listinfo/dysphagia
End of Dysphagia Digest, Vol 16, Issue 14
*****************************************
_______________________________________________
Dysphagia mailing list
Dysphagia@b9.com
http://lists.b9.com/mailman/listinfo/dysphagia
_______________________________________________
Dysphagia mailing list
Dysphagia@b9.com
http://lists.b9.com/mailman/listinfo/dysphagia
Dr I Campbell-Taylor
Clinical Neuroscientist
Exclusive Distributor:
www.interactivetherapy.com
|
|