[Dysphagia] New medication for PD

[eripley at yahoo.com (Irene Campbell-Taylor)]

This transdermal medication for PD may make Tx easier:
  http://www.medscape.com/viewprogram/6153_pnt
  One of the future forms of therapy we are looking at is different ways of giving the drugs to the patients. We have been using oral medications for years and years for Parkinson's disease. Over the last couple of years we have an injectable form, the short acting apomorphine. In the next few months you will see a new delivery system in Parkinson's disease, which is going to be a transdermal system. When you look at the transdermal system, it is pretty much composed of 3 layers. You have a film, you have self-adhesive, which basically has the loaded matrix, and you have a release liner. This pretty much ends up being a patch that is put on the skin and releases the medication that is absorbed through the skin, and provides more constant levels. Rotigotine is a dopamine agonist that will be available as a patch form.Rotigotine has been looked at in pharmacokinetic studies, and if the patch is applied in the abdomen part, shoulder, upper arm, thigh, hip, or flank -- so
 pretty much wherever in the body the patient can apply it -- the pharmacokinetics show that it is well absorbed through all these sites, produces a much more constant level in the blood stream, and here if you look at 24 hours, the levels are pretty constant throughout the day.
   


Dr I Campbell-Taylor
Clinical Neuroscientist
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www.interactivetherapy.com